Chengdu Biopurify Phytochemicals Ltd.

Product name: Alpha Cyperone
Synonym name: (+)-Alpha Cyperone; 4,11-Selinadien-3-one; (-)-Alpha Cyperone, 23665-61-4
Catalogue No.: BP0152
Cas No.: 473-08-5
Formula: C₁₅H₂₂O
Mol Weight: 218.34
Botanical Source: Cyperus rotundus (nutgrass), Cyperus scariosus and Juniperus horizontalis
Physical Description: Oil
Type of Compound: Sesquiterpenoids

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle

Storage: Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage.
Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.

The product could be supplied from milligrams to grams, up to kilograms
Inquire for bulk scale.

Descriptions:
Alpha-cyperone, a major active compound of Cyperus rotundus, has anti-inflammatory effects with the down-regulation of COX-2 and IL-6 via the negative regulation of the NFκB pathway in LPS-stimulated RAW 264.7 cells.[1]
In the presence of subinhibitory concentrations of alpha-cyperone, Hla production was markedly inhibited, and alpha-cyperone protects lung cells from Hla-induced injury , indicate that alpha-cyperone is a promising inhibitor of Hla production by S. aureus and protects lung cells from this bacterium, it may provide the basis for a new strategy to combat S. aureus pneumonia.[2]
Alpha-cyperone inhibits the expression of inflammatory and coagulant mediators via mitogen-activated protein kinase (MAPKs) and NF-kappa B signaling pathways, it may contribute to future research on the action mechanisms , as well as therapy for inflammation- or coagulation-related diseases.[3]

References:
[1] Jung S H, Su J K, Jun B G, et al. J Ethnopharmacol, 2013, 147(1):208-14.
[2] Luo M. J Microbiol Biotech. 2012, 22(8):1170-6.
[3] Fan, Qiao-Jia, Jiang, et al. Immunopharm Immunot, 2013, 35(2):215-24.
[4] Liang C, Luo Y, Zhong Z, et al. J Chinese Medicinal Materials, 2004, 27(8):578-9.